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Diagnostics Simplified

What is APTAMER?

Aptamers Aptamers are short DNA or RNA strands made in the lab. These DNA and RNA strands are folded into unique shapes that let them bind to other molecules through several molecular interactions. Because they are made in a lab, they have consistent quality, no animal ethics concerns, and are easy to scale up.

Aptamers can also be modified to improve their stability and shelf life. Aptamers tolerate heat well too, they can unfold and refold without losing function, and can be designed to target many types of molecules—from disease markers and microbes to environmental contaminants. Overall, aptamers are cheaper to produce than antibodies and offer a flexible, reliable option for diagnostics and sensing.

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What is APTCAD?

APTCAD, or Aptamer Computer Aided Design, is BIOGENES’ proprietary in-silico platform for designing synthetic antibody alternatives called aptamers, eliminating the need for animal-derived antibodies. Aptamers are short 30–100 base oligonucleotide sequences engineered to bind specifically to targets such as proteins, peptides, hormones, and small molecules

They function by folding into unique 3D shapes that attach to targets through hydrogen bonds and surface charge interactions. APTCAD guides the multi-step design process that generates these highly specific and effective binding molecules.

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